Can You Get Kidney Cancer from Smoking?

by Dr Chirag Bhirud | March 14, 2025

Did you know that smoking is one of the leading causes of kidney cancer?

Most of us link smoking with lung problems or heart disease, but its impact on your kidneys often flies under the radar. Here’s the worrying part: smoking doesn’t just damage your lungs; it directly contributes to kidney cancer.

Raising awareness is crucial because kidney cancer is one of the top 10 cancers in both men and women worldwide. Understanding the science behind this connection could be life-saving.

This guide will take you through the basics of kidney cancer, how smoking is a major risk factor, prevention tips, and what to look out for in terms of symptoms. Ready? Let’s get started.

What is Kidney Cancer?

Kidney cancer is a disease in which kidney cells grow out of control and form tumors. These vital organs, located on either side of your spine, filter waste from your blood and produce urine. When their cells become abnormal, they can hurt not just your kidneys but your overall health.

The most common type of kidney cancer is renal cell carcinoma (RCC). It accounts for about 85% of cases. Other less common forms include transitional cell carcinoma and Wilms’ tumor (more common in children).

→ Who is at Risk?

While kidney cancer can happen to anyone, certain factors increase your risk, such as:

    • Being over 50 years old
    • Family history of kidney cancer
    • High blood pressure
    • Long-term use of certain medications
    • Obesity

And yes, smoking is one of the biggest risk factors, as we’ll explore below.

Does Smoking Cause Kidney Cancer?

Yes, Smoking has been scientifically proven to raise the risk of kidney cancer. The research is clear: Smokers are up to 50% more likely to develop kidney cancer than non-smokers. Among heavy smokers, this risk can be even higher.

→ Scientific Explanation

When you inhale cigarette smoke, you’re taking in harmful chemicals like benzene, cadmium, and polycyclic aromatic hydrocarbons. These chemicals travel through your bloodstream and are filtered by your kidneys. Over time, they can damage kidney cells, cause mutations in their DNA, and promote tumor growth.

For example, carcinogens in tobacco smoke cause breaks and errors in cell replication, making it easier for cancerous cells to form. Damaged cells can eventually grow uncontrollably, leading to cancer.

Dr-Chirag-Bhirud

How Does Smoking Increase Kidney Cancer Risk?

Here’s what happens to your kidneys when you smoke:

1. Chemical Exposure

Cigarettes are loaded with harmful carcinogens. Chemicals like benzene and cadmium are filtered through the kidneys, damaging them with every puff. Over time, this toxic buildup makes kidney cells more prone to cancer-causing mutations.

2. Reduced Oxygen Supply

Smoking constricts your blood vessels, including those leading to the kidneys. This reduces oxygen supply and increases wear and tear on kidney tissues. Damaged kidneys are less effective at filtering toxins, creating a vicious cycle.

3. Immune System Suppression

A weaker immune system gives cancerous cells a better chance to grow without being detected. Smokers often experience hampered immunity, leaving room for tumors.

4. Increased Blood Pressure and Kidney Damage

Nicotine raises blood pressure, and chronic high blood pressure is a leading cause of kidney damage. Over time, damaged kidneys have a harder time sustaining healthy function, making them vulnerable to cancer.

Other Kidney Diseases Linked to Smoking

Even if kidney cancer isn’t on your radar, smoking can still wreak havoc on your kidneys in other ways. Here are a few notable examples:

    • Chronic Kidney Disease (CKD): Damaged kidneys gradually lose their ability to filter blood, often leading to CKD over time.
    • Kidney Stones: Smoking raises the likelihood of developing painful kidney stones.
    • Kidney Failure: Long-term smoking increases the risk of total kidney failure, which can be life-threatening.

Signs and Symptoms of Kidney Cancer

Although early-stage kidney cancer may have no noticeable symptoms, here are some red flags to watch for:

    • Blood in your urine (called hematuria)
    • Persistent lower back pain, usually on one side
    • Unexplained weight loss
    • Fatigue and general weakness
    • High blood pressure, especially if you’ve noticed no previous issues

If you experience any of these, it’s crucial to consult a Cancer Specialist in Pune immediately.

Who is at Higher Risk?

While smoking is a major contributor, other groups face an elevated risk:

    • Heavy Smokers: The more you smoke, the higher your risk.
    • People With a Family History: Genetics can also increase vulnerability.
    • Those With High Blood Pressure or Diabetes: Both conditions stress your kidneys.
    • Workers Exposed to Chemicals: Jobs involving prolonged exposure to toxic substances (like cadmium in factories) are risky.

How to Reduce Kidney Cancer Risk if You Smoke?

1. Quit Smoking

The single most effective way to lower your risk is to stop smoking. Here’s a rough timeline of what happens when you quit:

    • Within Weeks: Your blood pressure and oxygen levels improve.
    • Within a Year: Your risk of kidney cancer starts to decrease.
    • Over Time: After 10–15 years, an ex-smoker’s risk approaches that of someone who never smoked.

2. Diet and Lifestyle Changes

Adopting healthy habits can help reduce your risk further, even if you’ve smoked for years:

    • Antioxidant-Rich Foods: Include leafy greens, berries, and nuts to combat oxidative stress.
    • Stay Hydrated: Proper hydration supports kidney health. Aim for 8–10 glasses of water daily.

3. Regular Screenings and Check-Ups

Early detection saves lives. If you’re in a high-risk category, regular check-ups are crucial. Doctors may recommend:

    • CT Scans or MRIs: To identify any potential tumors.
    • Urine Tests: These check for blood or abnormal proteins.

FAQs

1. Can smoking one cigarette a day cause kidney cancer?

Even light smoking increases your risk, though heavy smoking is worse. No level of smoking is entirely “safe.”

 

2. Does quitting smoking lower kidney cancer risk?

Absolutely! The sooner you quit, the more you reduce your risk.

 

3. How many years of smoking cause kidney cancer?

There’s no exact number, but the risk builds with prolonged exposure. Heavy smokers are at the most significant risk over decades.

 

4. What percentage of kidney cancer is caused by smoking?

Around 20-30% of kidney cancer cases are directly linked to smoking, particularly in men.

 

5. Is vaping safer for kidney health?

Vaping isn’t completely safe, as it still introduces harmful chemicals into the body, though risks may be lower compared to traditional cigarettes.

 

6. Can secondhand smoke increase kidney cancer risk?

Yes, regular exposure to secondhand smoke can also influence kidney cancer risk.

 

Wrapping It Up

Smoking significantly raises your risk of kidney cancer by exposing your kidneys to harmful chemicals, reducing oxygen supply, weakening your immune system, and increasing blood pressure.

But here’s the good news: quitting smoking and adopting a healthy lifestyle can dramatically lower these risks.

If you or someone you know smokes, consider this a wake-up call. Take action today. Share this information, prioritize regular health screenings, and, most importantly, quit smoking to protect your kidneys and your overall well-being.

Dr. Chirag Bhirud emphasizes the importance of kidney health and encourages everyone to make healthier choices for a longer, healthier life.

Your kidneys work hard to keep you healthy. Isn’t it time you gave them a break? 🚭💙

If you have any further queries, please write to us.